

These sources include peer-reviewed studies and information from agencies such as the FDA and USDA, and the National Academy of Medicine. In addition the results of its expert testing, ConsumerLab uses only high-quality, evidence based, information sources. In addition, certain medications such as the immunosuppressant drug tacrolimus, oral contraceptives, estrogen replacement therapy, and loop and thiazide diuretics can deplete levels of magnesium in the body ( Niederstadt, Transplant Proc 1997 Blum, Harefuah 1991 Kuller, Am J Epidemiol 1985), while antacid medications including H2 blockers such as cimetidine (Tagamet), famotidine (Pepcid AC) and ranitidine (Zantac), and proton pump inhibitors such as esomeprazole (Nexium) and lansoprazole (Prevacid), may interfere with magnesium's laxative effects ( Kieboom, Pharmacoepidemiol Drug Saf 2018 Yamasaki, Eur Clin Pharmacol 2014).įor details, see the Cautions and Concerns section of the Magnesium Supplements Review.

In some cases, magnesium can still be taken, but only several hours before or after taking these drugs.īe aware that these interactions apply not only to magnesium in supplements but also in over-the-counter antacids and laxatives. On the other hand, one form of magnesium may increase the absorption of certain anti-diabetes drugs such as glibenclamide (DiaBeta, Micronase, Glynase) and glimepiride (Amaryl), potentially affecting blood sugar control ( Neuvonen, Br J Clin Pharmacol 1991 Kivisto, Clin Pharmacol Ther 1991).

Magnesium can decrease the absorption and effectiveness of numerous medications, including some common antibiotics such as tetracycline (Achromycin, Sumycin), demeclocycline (Declomycin), doxycycline (Vibramycin), minocycline (Minocin), ciprofloxacin (Cipro), levofloxacin (Levaquin), moxifloxacin (Avelox) and ofloxacin (Floxin) ( NIH 2017 Cipro Prescribing Information 2016) certain statin drugs such as rosuvastatin (Crestor) and atorvastatin (Lipitor) ( Martin, Curr Med Res Opin 2008) sotalol (Betapace, Sotylize, Sorine), a drug prescribed for atrial fibrillation ( Betapace Prescribing Information 2010) gabapentin (Neurontin), a drug prescribed for seizures ( Neurontin Prescribing Information 2017) and levothyroxine (Synthroid), a drug prescribed for thyroid disorders ( Synthroid Prescribing Information 2017).
